Posaconazole Impurity

Posaconazole Impurity - Names and Identifiers

Name	Posaconazole iMpurity
Synonyms	Posaconazole IMP ent-Posaconazole Posaconazole IMP Posaconazole iMpurity Posaconazole Impurity S 2,6-Difluoro Posaconazole (3R,5S,2R,3R)-posaconazole Posaconazole Diastereoisomer 14 Posaconazole Diastereoisomer 10
CAS	1229428-89-0

Posaconazole Impurity - Physico-chemical Properties

Molecular Formula	C37H42F2N8O4
Molar Mass	700.79
Density	1.36±0.1 g/cm3(Predicted)
Boling Point	850.7±75.0 °C(Predicted)
pKa	14.72±0.20(Predicted)

Posaconazole Impurity - Introduction

Posaconazole is a broad-spectrum antifungal drug, and its impurities refer to other chemicals related to the molecular structure of posaconazole.

The properties of Posaconazole iMpurity can vary according to specific types. Common Posaconazole iMpurity includes in-situ deactivation products, oxidation/reduction products, cyclization products, etc. on the chemical structure. These impurities are mostly minor changes in the structure of posaconazole and are considered inevitable in purity analysis and quality control.

The use of Posaconazole iMpurity is for analysis and monitoring in drug development and quality control. By analyzing the generation, change and content of impurities, the purity, stability and quality of posaconazole can be evaluated.

Methods for preparing Posaconazole iMpurity include chemical synthesis and biotransformation. Common methods include chemical modification of the posaconazole molecule or production of specific impurities by means of microbial fermentation or bioconversion.

Last Update：2024-04-09 19:05:55